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The complex interplay of diet, xenobiotics, and microbial metabolism in the gut: Implications for clinical outcomes

The complex interplay of diet, xenobiotics, and microbial metabolism in the gut: Implications for clinical outcomes

by Igen BioLab Group | Oct 1, 2020 | News, Publications

From digestion to pathogen resistance and immune system development, the gut microbiota and its collection of microbial genes are redefining what it means to be human. Despite tremendous advances in this field, there is still a limited understanding of how microbial...
Rat study shows gut microbes play a role in colon cancer susceptibility

Rat study shows gut microbes play a role in colon cancer susceptibility

by Igen BioLab Group | Aug 19, 2020 | News, Publications

The microscopic organisms that live in our gut do more than help us digest food. A new study in rats bolsters a growing body of evidence that the complex mix of microorganisms found in the gut, known as gut microbiota, could influence a person’s likelihood of...
Genome and sequence determinants governing the expression of horizontally acquired DNA in bacteria

Genome and sequence determinants governing the expression of horizontally acquired DNA in bacteria

by Igen BioLab Group | Jun 15, 2020 | News, Publications

While horizontal gene transfer is prevalent across the biosphere, the regulatory features that enable expression and functionalization of foreign DNA remain poorly understood. Here, we combine high-throughput promoter activity measurements and large-scale genomic...

Recent Posts

  • Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade
  • A synthetic consortium of 100 gut commensals modulates the composition and function in a colon model of the microbiome of elderly subjects
  • ‘Multi-kingdom dialogue’ between internal, external microbiota
  • Gut microbiota-derived short-chain fatty acids promote prostate cancer growth via IGF-1 signaling
  • Diet alters entero-mammary signaling to regulate the breast microbiome and tumorigenesis
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