by Igen BioLab Group | Jan 22, 2021 | News, Publications
Microbial dysbiosis has been implicated in the pathogenesis of oral cancer. We analyzed the compositional and metabolic profile of the bacteriome in three specific niches in oral cancer patients along with controls using 16SrRNA sequencing (Illumina Miseq) and DADA2...
by Igen BioLab Group | Jan 21, 2021 | News, Publications
The gut microbiome can influence the development of tumors and the efficacy of cancer therapeutics; however, the multiomics characteristics of antitumor bacterial strains have not been fully elucidated. In this study, we integrated metagenomics, genomics and...
by Igen BioLab Group | Jan 19, 2021 | News, Publications
This work describes a new procedure that allows the targeted modification of the human gut microbiota by using antibodies raised against bacterial surface-associated proteins specific to the microorganism of interest. To this end, a polyclonal antibody recognising the...
by Igen BioLab Group | Jan 14, 2021 | News, Publications
An increased risk of developing colorectal cancer (CRC) and other types of tumor is associated to Lynch syndrome (LS), an inherited condition caused by germline mutations in mismatch repair genes. We selected a cohort of LS patients that had developed CRC and had...
by Igen BioLab Group | Dec 22, 2020 | News, Publications
The type and abundance of bacteria found in the mouth may be linked to lung cancer risk in non-smokers, finds the first study of its kind, published online in the journal Thorax. Fewer species and high numbers of particular types of bacteria seem to be linked to...
