Publications
New link between diet, intestinal stem cells and disease discovered
Using a mouse model, the researchers investigated the effects of a high-sugar and high-fat diet and compared it with a control group.
Cleveland Clinic study links gut microbiome and aggressive prostate cancer
Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk.
Chronic liver disease enables gut Enterococcus faecalis colonization to promote liver carcinogenesis
The study shows that Enterococcus faecalis is abundant in the microbiota of patients with hepatitis C virus-related chronic liver disease.
Intestinal microbiota drive CRPC
Data published in Science provide evidence that the intestinal microbiota can drive prostate cancer towards castration resistance by providing an alternative source of androgens.
Hormone-producing bacteria drive prostate cancer
During androgen-deprivation therapy, certain bacteria in the gut can synthesize androgens, thereby promoting tumor progression and therapy resistance.
Mechanisms underlying interactions between two abundant oral commensal bacteria
Complex polymicrobial biofilm communities are abundant in nature particularly in the human oral cavity where their composition and fitness can affect health.
Gut Bacteria may Fuel prostate Cancer Treatment Resistance
A mainstay of treatment for prostate cancer is to deprive it of androgens, the hormones that make it grow.
Gut microbiota and short-chain fatty acid alterations in cachectic cancer patients
Cancer cachexia is characterized by a negative energy balance, muscle and adipose tissue wasting, insulin resistance, and systemic inflammation.
Targeting fungi for Crohn’s disease?
This article, written by Andreu Prados, discusses the discovery of a fungus that delays wound healing in mice and is enriched in the inflamed tissue of patients with Crohn’s disease.