News
Distinct respiratory microbiota associates with lung cancer clinicopathological characteristics
Commensal microbiota dysbiosis is associated with the development of lung cancer. The current studies about composition of respiratory microbiota in lung cancer patients yielded inconsistent results. This study aimed to examine the association between airway...
MD Anderson and Federation Bio announce collaboration to develop novel microbiome treatment for patients with immunotherapy-resistant cancers
The University of Texas MD Anderson Cancer Center and Federation Bio today announced a strategic collaboration to design and manufacture a complex, synthetic microbial consortium with the goal of expanding the number of cancer patients who respond to immunotherapy....
Intratumor microbiota: a novel tumor component
Bacteria have been found in tumors for over 100 years, but the irreproducibility of experiments on bacteria, the limitations of science and technology, and the contamination of the host environment have severely hampered most research into the role of bacteria in...
Press Releases
Distinct respiratory microbiota associates with lung cancer clinicopathological characteristics
Commensal microbiota dysbiosis is associated with the development of lung cancer. The current studies about composition of respiratory microbiota in lung cancer patients yielded inconsistent results. This study aimed to examine the association between airway...
MD Anderson and Federation Bio announce collaboration to develop novel microbiome treatment for patients with immunotherapy-resistant cancers
The University of Texas MD Anderson Cancer Center and Federation Bio today announced a strategic collaboration to design and manufacture a complex, synthetic microbial consortium with the goal of expanding the number of cancer patients who respond to immunotherapy....
Intratumor microbiota: a novel tumor component
Bacteria have been found in tumors for over 100 years, but the irreproducibility of experiments on bacteria, the limitations of science and technology, and the contamination of the host environment have severely hampered most research into the role of bacteria in...
Events
Microbiota and Cancer: The Emerging Beneficial Role of Bifidobacteria in Cancer Immunotherapy
Many intestinal bacteria are believed to be involved in various inflammatory and immune processes that influence tumor etiology because of their metabolic properties and their ability to alter the microbiota homeostasis. Although many functions of the microbiota are...
The interplay between the intratumoural microbiome, the type of cancer inflammation and the response to immunotherapy
Dr Santiago Zelenay, CRUK Manchester Institute, UK & Dr Ravid Straussman, Weizmann Institute, Israel We are pleased to announce this exciting new PhD opportunity at the Cancer Research UK Manchester Institute and the Weizmann Institute, Israel. Immunotherapies...
Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy
Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in human health. An altered microbiome can be associated with complex diseases. Intratumoral microbial components are found in multiple tumor tissues and are closely...
Publications
Interplay Between Oncomicrobes, the Microbiota and the Immune System: Impact on Responses to Cancer Immunotherapy
Cancer immunotherapies harness the power of the immune system to target cancer cells that express tumor-associated antigens. Immune checkpoint inhibitors, such as monoclonal antibodies against inhibitory T cell receptors, i.e., PD-1/PD-L1 and CTLA-4, allow cancer...
Combined Microbiome and Metabolome Analysis Reveals a Novel Interplay Between Intestinal Flora and Serum Metabolites in Lung Cancer
As the leading cause of cancer death, lung cancer seriously endangers human health and quality of life. Although many studies have reported the intestinal microbial composition of lung cancer, little is known about the interplay between intestinal microbiome and...
Alterations of lung microbiota in patients with non-small cell lung cancer
The role of lung microbiota in non-small cell lung cancer remains unclear. We investigated the characteristics and functional roles of lung microbiota in non-small cell lung cancer.Bronchoalveolar lavage fluid samples were obtained from patients with non-small cell...
