The interplay between the intratumoural microbiome, the type of cancer inflammation and the response to immunotherapy
Dr Santiago Zelenay, CRUK Manchester Institute, UK & Dr Ravid Straussman, Weizmann Institute, Israel We are pleased to announce this exciting new PhD opportunity at the Cancer Research UK Manchester Institute and the Weizmann Institute, Israel. Immunotherapies...
Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy
Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in human health. An altered microbiome can be associated with complex diseases. Intratumoral microbial components are found in multiple tumor tissues and are closely...
Microbiota contributions
Intratumoral microbiota have been described in various human cancers. In Nature, Bullman and colleagues use in situ spatial-profiling technologies and single-cell RNA sequencing (scRNA-seq) to map host–bacterial interactions within the tumour microenvironment. In oral...
The microbiome and human cancer
BACKGROUND: Historical accounts linking cancer and microbes date as early as four millennia ago. Post establishment of the germ theory of infectious diseases, clinical research of microbial influences on cancer began in 1868, when William Busch reported spontaneous...
