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Differences in the bacteriome of swab, saliva, and tissue biopsies in oral cancer

Differences in the bacteriome of swab, saliva, and tissue biopsies in oral cancer

by Igen BioLab Group | Jan 22, 2021 | News, Publications

Microbial dysbiosis has been implicated in the pathogenesis of oral cancer. We analyzed the compositional and metabolic profile of the bacteriome in three specific niches in oral cancer patients along with controls using 16SrRNA sequencing (Illumina Miseq) and DADA2...
Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice

Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice

by Igen BioLab Group | Jan 21, 2021 | News, Publications

The gut microbiome can influence the development of tumors and the efficacy of cancer therapeutics; however, the multiomics characteristics of antitumor bacterial strains have not been fully elucidated. In this study, we integrated metagenomics, genomics and...
Precision modification of the human gut microbiota targeting surface-associated proteins

Precision modification of the human gut microbiota targeting surface-associated proteins

by Igen BioLab Group | Jan 19, 2021 | News, Publications

This work describes a new procedure that allows the targeted modification of the human gut microbiota by using antibodies raised against bacterial surface-associated proteins specific to the microorganism of interest. To this end, a polyclonal antibody recognising the...
New finding in microbiota of colorectal cancer patients

New finding in microbiota of colorectal cancer patients

by Igen BioLab Group | Jan 14, 2021 | News, Publications

An increased risk of developing colorectal cancer (CRC) and other types of tumor is associated to Lynch syndrome (LS), an inherited condition caused by germline mutations in mismatch repair genes. We selected a cohort of LS patients that had developed CRC and had...
Type and abundance of mouth bacteria linked to lung cancer risk in non-smokers

Type and abundance of mouth bacteria linked to lung cancer risk in non-smokers

by Igen BioLab Group | Dec 22, 2020 | News, Publications

The type and abundance of bacteria found in the mouth may be linked to lung cancer risk in non-smokers, finds the first study of its kind, published online in the journal Thorax. Fewer species and high numbers of particular types of bacteria seem to be linked to...
Unexpected guests in the tumor microenvironment: microbiome in cancer

Unexpected guests in the tumor microenvironment: microbiome in cancer

by Igen BioLab Group | Dec 18, 2020 | News, Publications

Although intestinal microbiome have been established as an important biomarker and regulator of cancer development and therapeutic response, less is known about the role of microbiome at other body sites in cancer. Emerging evidence has revealed that the local...
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Recent Posts

  • Differences in the bacteriome of swab, saliva, and tissue biopsies in oral cancer
  • Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice
  • Precision modification of the human gut microbiota targeting surface-associated proteins
  • New finding in microbiota of colorectal cancer patients
  • Type and abundance of mouth bacteria linked to lung cancer risk in non-smokers
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