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Metagenomic Analyses Reveal Distinct Gut Microbiota Signature for Predicting the Neoadjuvant Chemotherapy Responsiveness in Breast Cancer Patients

Metagenomic Analyses Reveal Distinct Gut Microbiota Signature for Predicting the Neoadjuvant Chemotherapy Responsiveness in Breast Cancer Patients

by Igen BioLab Group | Apr 29, 2022 | News, Publications

Growing evidence supports the modulatory role of human gut microbiome on neoadjuvant chemotherapy (NAC) efficacy. However, the relationships among the gut microbiome, tumor-infiltrating lymphocytes (TILs), and NAC response for breast cancer (BC) patients remain...
Deciphering the Microbiome-Immunity-Cancer Axis

Deciphering the Microbiome-Immunity-Cancer Axis

by Igen BioLab Group | Apr 29, 2022 | News, Publications

Trillions of microbes inhabit human body surfaces and cavities and interact with the host constantly. Recently, it came to light that the microbiota is a critical regulator of tumorigenesis and impacts outcomes of various cancer therapies. Pathogenic bacteria can...
Targeting the gut and tumor microbiota in cancer

Targeting the gut and tumor microbiota in cancer

by Igen BioLab Group | Apr 29, 2022 | News, Publications

Microorganisms within the gut and other niches may contribute to carcinogenesis, as well as shaping cancer immunosurveillance and response to immunotherapy. Our understanding of the complex relationship between different host-intrinsic microorganisms, as well as the...
Healthy gut microbiome improves success of cancer treatment

Healthy gut microbiome improves success of cancer treatment

by Igen BioLab Group | Mar 28, 2022 | News, Publications

The composition of the gut microbiome has been associated with clinical responses to immune checkpoint inhibitor (ICI) treatment, but there is limited consensus on the specific microbiome characteristics linked to the clinical benefits of ICIs. We performed shotgun...
Nasopharyngeal Microbiota as an early severity biomarker in COVID-19 hospitalised patients

Nasopharyngeal Microbiota as an early severity biomarker in COVID-19 hospitalised patients

by Igen BioLab Group | Mar 15, 2022 | News, Publications

This study aimed to analyse the diversity and taxonomic composition of the nasopharyngeal microbiota, to determine its association with COVID-19 clinical outcome. To study the microbiota, we utilized 16S rRNA sequencing of 177 samples that came from a retrospective...
The role of gut microbiome in cancer genesis and cancer prevention

The role of gut microbiome in cancer genesis and cancer prevention

by Igen BioLab Group | Mar 11, 2022 | News, Publications

Cancer is the second leading cause of fatalities at the global level, and the involvement of microbes in several diseases, including cancer is well known. The gut microbiome is known to have an essential role in the regulation of the host’s health and...
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Recent Posts

  • Metagenomic Analyses Reveal Distinct Gut Microbiota Signature for Predicting the Neoadjuvant Chemotherapy Responsiveness in Breast Cancer Patients
  • Deciphering the Microbiome-Immunity-Cancer Axis
  • Targeting the gut and tumor microbiota in cancer
  • Healthy gut microbiome improves success of cancer treatment
  • Nasopharyngeal Microbiota as an early severity biomarker in COVID-19 hospitalised patients
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