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Microbiota contributions

Microbiota contributions

Intratumoral microbiota have been described in various human cancers. In Nature, Bullman and colleagues use in situ spatial-profiling technologies and single-cell RNA sequencing (scRNA-seq) to map host–bacterial interactions within the tumour microenvironment. In oral...

The microbiome and human cancer

The microbiome and human cancer

BACKGROUND: Historical accounts linking cancer and microbes date as early as four millennia ago. Post establishment of the germ theory of infectious diseases, clinical research of microbial influences on cancer began in 1868, when William Busch reported spontaneous...

Unhealthy Gut Helps Breast Cancer Spread, Research Reveals

Unhealthy Gut Helps Breast Cancer Spread, Research Reveals

An unhealthy gut triggers changes in normal breast tissue that helps breast cancer spread to other parts of the body, new research from UVA Cancer Center reveals. The gut microbiome – the collection of microbes that naturally live inside us – can be disrupted by poor...

Human Microbiome and Cancer

Human Microbiome and Cancer

The microbiome refers to the collection of all of the gene sequences from a community of microbes in the human body. High-throughput DNA amplification and sequencing technologies to characterize the microbial communities provide data for investigations of microbial...