Gut microbiota in colorectal cancer development and therapy
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC is its intimate association with the gut microbiota, which forms an essential part of the tumour microenvironment. Research over the past decade has established that dysbiosis of...
Study identifies how microbiome may affect pancreatic cancer outcomes
Research finds certain species elevated in long-term survivors Even as pancreatic cancer treatments improve, only about 9% of patients survive past five years. Researchers have searched unsuccessfully to find genetic differences that explain why some patients survive...
An integrated tumor, immune and microbiome atlas of colon cancer
The lack of multi-omics cancer datasets with extensive follow-up information hinders the identification of accurate biomarkers of clinical outcome. In this cohort study, we performed comprehensive genomic analyses on fresh-frozen samples from 348 patients affected by...
