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A synthetic consortium of 100 gut commensals modulates the composition and function in a colon model of the microbiome of elderly subjects

A synthetic consortium of 100 gut commensals modulates the composition and function in a colon model of the microbiome of elderly subjects

by Igen BioLab Group | Jul 14, 2021 | News, Publications

Administration of cultured gut isolates holds promise for modulating the altered composition and function of the microbiota in older subjects, and for promoting their health. From among 692 initial isolates, we selected 100 gut commensal strains (MCC100) based on...
‘Multi-kingdom dialogue’ between internal, external microbiota

‘Multi-kingdom dialogue’ between internal, external microbiota

by Igen BioLab Group | Jul 7, 2021 | News, Publications

The billions of organisms living on body surfaces such as the skin of mammals -collectively called microbiota- communicate with each other and the host immune system in a sophisticated network. According to the study, viruses integrated in the host genome, remnants of...
Prevotella diversity, niches and interactions with the human host

Prevotella diversity, niches and interactions with the human host

by Igen BioLab Group | Jun 3, 2021 | News, Publications

The genus Prevotella includes more than 50 characterized species that occur in varied natural habitats, although most Prevotella spp. are associated with humans. In the human microbiome, Prevotella spp. are highly abundant in various body sites, where they are key...
Modulation of immune responses to vaccination by the microbiota: implications and potential mechanisms

Modulation of immune responses to vaccination by the microbiota: implications and potential mechanisms

by Igen BioLab Group | May 20, 2021 | News, Publications

The need for highly effective vaccines that induce robust and long-lasting immunity has never been more apparent. However, for reasons that are still poorly understood, immune responses to vaccination are highly variable between different individuals and different...
The role of gut microbiota in cancer treatment: friend or foe?

The role of gut microbiota in cancer treatment: friend or foe?

by Igen BioLab Group | May 7, 2021 | News, Publications

The gut microbiota has been implicated in cancer and shown to modulate anticancer drug efficacy. Altered gut microbiota is associated with resistance to chemo drugs or immune checkpoint inhibitors (ICIs), whereas supplementation of distinct bacterial species restores...
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Recent Posts

  • Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade
  • A synthetic consortium of 100 gut commensals modulates the composition and function in a colon model of the microbiome of elderly subjects
  • ‘Multi-kingdom dialogue’ between internal, external microbiota
  • Gut microbiota-derived short-chain fatty acids promote prostate cancer growth via IGF-1 signaling
  • Diet alters entero-mammary signaling to regulate the breast microbiome and tumorigenesis
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