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Designer probiotic treatment for cancer immunotherapy

Designer probiotic treatment for cancer immunotherapy

by Igen BioLab Group | Feb 25, 2020 | News, Publications

Checkpoint inhibitors have revolutionized cancer therapy but only work in a subset of patients and can lead to a multitude of toxicities, suggesting the need for more targeted delivery systems. Because of their preferential colonization of tumors, microbes are a...
Milestones in gut microbiome science in 2019

Milestones in gut microbiome science in 2019

by Igen BioLab Group | Jan 7, 2020 | News, Publications

The human microbiome has not only captured the attention of scientists, but also of health professionals and the lay press. Although initial studies focused on characterizing the intestinal microbiome in the context of health and disease and the influence of...
Investigating the human intestinal mucus barrier up-close and personal

Investigating the human intestinal mucus barrier up-close and personal

by Igen BioLab Group | Dec 30, 2019 | News, Publications

The mucus layer in the human colon protects against commensal bacteria and pathogens, and defects in its unique bilayered structure contribute to intestinal disorders, such as ulcerative colitis. However, our understanding of colon physiology is limited by the lack of...
Intestinal microbiota and colorectal carcinoma

Intestinal microbiota and colorectal carcinoma

by Igen BioLab Group | Dec 20, 2019 | News, Publications

Implications for pathogenesis, diagnosis, and therapy  Colorectal cancer (CRC) is one of the most frequently diagnosed cancers and leading cause of cancer-related deaths worldwide. In recent years, there has been a growing realization that lifestyle plays a major role...
Gut microbiota imbalance promotes the onset of colorectal cancer

Gut microbiota imbalance promotes the onset of colorectal cancer

by Igen BioLab Group | Nov 25, 2019 | News, Publications

The gastroenterology team at Henri-Mondor AP-HP Hospital and University Paris-Est Créteil, led by Professor Iradj Sobhani, together with teams from Inserm and the Institut Pasteur Molecular Microbial Pathogenesis Unit (U1202), led by Professor Philippe Sansonetti...
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Recent Posts

  • Detection and analysis of lung microbiota in mice with lung cancer lacking the NLRP3 gene
  • Special Issue “Microbiome in Cancer: Role in Carcinogenesis and Impact in Therapeutic Strategies”
  • Microbiota contributions
  • Gastric Microbiome Alterations Are Associated with Decreased CD8+ Tissue-Resident Memory T Cells in the Tumor Microenvironment of Gastric Cancer
  • The microbiome and human cancer
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