Milestones in gut microbiome science in 2019
The human microbiome has not only captured the attention of scientists, but also of health professionals and the lay press. Although initial studies focused on characterizing the intestinal microbiome in the context of health and disease and the influence of...
Investigating the human intestinal mucus barrier up-close and personal
The mucus layer in the human colon protects against commensal bacteria and pathogens, and defects in its unique bilayered structure contribute to intestinal disorders, such as ulcerative colitis. However, our understanding of colon physiology is limited by the lack of...
Intestinal microbiota and colorectal carcinoma
Implications for pathogenesis, diagnosis, and therapy Colorectal cancer (CRC) is one of the most frequently diagnosed cancers and leading cause of cancer-related deaths worldwide. In recent years, there has been a growing realization that lifestyle plays a major role...
