Healthy gut microbiome improves success of cancer treatment
The composition of the gut microbiome has been associated with clinical responses to immune checkpoint inhibitor (ICI) treatment, but there is limited consensus on the specific microbiome characteristics linked to the clinical benefits of ICIs. We performed shotgun...
The role of gut microbiome in cancer genesis and cancer prevention
Cancer is the second leading cause of fatalities at the global level, and the involvement of microbes in several diseases, including cancer is well known. The gut microbiome is known to have an essential role in the regulation of the host’s health and...
Intestinal microbiota signatures of clinical response and immune-related adverse events in melanoma patients treated with anti-PD-1
Ample evidence indicates that the gut microbiome is a tumor-extrinsic factor associated with antitumor response to anti-programmed cell death protein-1 (PD-1) therapy, but inconsistencies exist between published microbial signatures associated with clinical outcomes....
