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Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice

Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice

by Igen BioLab Group | Jan 21, 2021 | Publications

The gut microbiome can influence the development of tumors and the efficacy of cancer therapeutics; however, the multiomics characteristics of antitumor bacterial strains have not been fully elucidated. In this study, we integrated metagenomics, genomics and...
Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice

Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice

by Igen BioLab Group | Aug 10, 2020 | Publications

Prenatal and early life bacterial colonisation is thought to play a major role in shaping the immune system. Furthermore, accumulating evidence links early life exposures to the risk of developing IBD later in life. We aimed to assess the effect of maternal IBD on the...
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