Altering the microbiome for immunotherapy-resistant urological tumors-An intriguing but still early concept
The intestinal microbiome may play an important role in immunomodulation and affect treatment responses to immune checkpoint inhibitor therapy in genitourinary malignancies. Characterizing this impact will require consensus and standardization of microbiome sample...
Chemo shown to upset gut microbes in cancer patients
The study led by infectious diseases expert and clinical microbiologist, Dr. Lito Papanicolas, assessed the gut health of men and women who underwent conventional chemotherapy on cancers, such as breast and lung cancer, without exposure toantibiotics. “We know...
Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health
Objective Gut microbial products are involved in regulation of host metabolism. In human and experimental studies, we explored the potential role of hippurate, a hepatic phase 2 conjugation product of microbial benzoate, as a marker and mediator of metabolic...
