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Adding single type of bacteria to gut microbiome boosted anti-tumor immunity in mice Peer-Reviewed Publication

Adding single type of bacteria to gut microbiome boosted anti-tumor immunity in mice Peer-Reviewed Publication

by Igen BioLab Group | Dec 9, 2021 | Publications

A bacterium common in the mouse gut microbiome can charge up the immune system to fight cancer cells in the colon, researchers from the University of Pittsburgh School of Medicine report today in the journal Immunity.    The study showed that bacterium Helicobacter...
Altering the microbiome for immunotherapy-resistant urological tumors-An intriguing but still early concept

Altering the microbiome for immunotherapy-resistant urological tumors-An intriguing but still early concept

by Igen BioLab Group | Sep 15, 2021 | Publications

The intestinal microbiome may play an important role in immunomodulation and affect treatment responses to immune checkpoint inhibitor therapy in genitourinary malignancies. Characterizing this impact will require consensus and standardization of microbiome sample...
Chemo shown to upset gut microbes in cancer patients

Chemo shown to upset gut microbes in cancer patients

by Igen BioLab Group | Aug 18, 2021 | Publications

The study led by infectious diseases expert and clinical microbiologist, Dr. Lito Papanicolas, assessed the gut health of men and women who underwent conventional chemotherapy on cancers, such as breast and lung cancer, without exposure toantibiotics. “We know...
Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health

Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health

by Igen BioLab Group | May 26, 2021 | Publications

Objective Gut microbial products are involved in regulation of host metabolism. In human and experimental studies, we explored the potential role of hippurate, a hepatic phase 2 conjugation product of microbial benzoate, as a marker and mediator of metabolic...
Gut microbiome pattern reflects healthy ageing and predicts survival in humans

Gut microbiome pattern reflects healthy ageing and predicts survival in humans

by Igen BioLab Group | Feb 25, 2021 | Publications

The gut microbiome has important effects on human health, yet its importance in human ageing remains unclear. In the present study, we demonstrate that, starting in mid-to-late adulthood, gut microbiomes become increasingly unique to individuals with age.  We leverage...
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