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A pilot study of the sequencing of the intestinal microbiota for colon cancer

A pilot study of the sequencing of the intestinal microbiota for colon cancer

by Igen BioLab Group | Jul 10, 2020 | Publications

The intestinal microbiota, composed by the microorganisms that live in our intestines, can give us information about our health, since its composition may depend on factors such as the diet, the lifestyle or our pathologies. Moreover, knowing what specific bacteria...
Re-evaluating the relationship between missing heritability and the microbiome

Re-evaluating the relationship between missing heritability and the microbiome

by Igen BioLab Group | Jun 18, 2020 | Publications

Human genome-wide association studies (GWASs) have recurrently estimated lower heritability estimates than familial studies. Many explanations have been suggested to explain these lower estimates, including that a substantial proportion of genetic variation and...
Genome and sequence determinants governing the expression of horizontally acquired DNA in bacteria

Genome and sequence determinants governing the expression of horizontally acquired DNA in bacteria

by Igen BioLab Group | Jun 15, 2020 | Publications

While horizontal gene transfer is prevalent across the biosphere, the regulatory features that enable expression and functionalization of foreign DNA remain poorly understood. Here, we combine high-throughput promoter activity measurements and large-scale genomic...

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