A bacterium common in the mouse gut microbiome can charge up the immune system to fight cancer cells in the colon, researchers from the University of Pittsburgh School of Medicine report today in the journal Immunity. The study showed that bacterium Helicobacter...
The dose-limiting side effect of the common colon cancer chemotherapeutic CPT-11 is severe diarrhea caused by symbiotic bacterial β-glucuronidases that reactivate the drug in the gut. We sought to target these enzymes without killing the commensal bacteria essential...
Cancer mutations can be caused by common gut bacteria carried by many people. This was demonstrated by researchers from the Hubrecht Institute (KNAW) and Princess Máxima Center in Utrecht, the Netherlands. By exposing cultured human mini-guts to a particular strain of...
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