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Adding single type of bacteria to gut microbiome boosted anti-tumor immunity in mice Peer-Reviewed Publication

Adding single type of bacteria to gut microbiome boosted anti-tumor immunity in mice Peer-Reviewed Publication

by Igen BioLab Group | Dec 9, 2021 | Publications

A bacterium common in the mouse gut microbiome can charge up the immune system to fight cancer cells in the colon, researchers from the University of Pittsburgh School of Medicine report today in the journal Immunity.    The study showed that bacterium Helicobacter...
Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

by Igen BioLab Group | Sep 1, 2020 | Publications

The dose-limiting side effect of the common colon cancer chemotherapeutic CPT-11 is severe diarrhea caused by symbiotic bacterial β-glucuronidases that reactivate the drug in the gut. We sought to target these enzymes without killing the commensal bacteria essential...
A common gut microbe secretes a carcinogen

A common gut microbe secretes a carcinogen

by Igen BioLab Group | Mar 2, 2020 | News, Publications

Cancer mutations can be caused by common gut bacteria carried by many people. This was demonstrated by researchers from the Hubrecht Institute (KNAW) and Princess Máxima Center in Utrecht, the Netherlands. By exposing cultured human mini-guts to a particular strain of...

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