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Unhealthy Gut Helps Breast Cancer Spread, Research Reveals

Unhealthy Gut Helps Breast Cancer Spread, Research Reveals

by Igen BioLab Group | Dec 7, 2022 | Events, News

An unhealthy gut triggers changes in normal breast tissue that helps breast cancer spread to other parts of the body, new research from UVA Cancer Center reveals. The gut microbiome – the collection of microbes that naturally live inside us – can be disrupted by poor...
Metagenomic Analyses Reveal Distinct Gut Microbiota Signature for Predicting the Neoadjuvant Chemotherapy Responsiveness in Breast Cancer Patients

Metagenomic Analyses Reveal Distinct Gut Microbiota Signature for Predicting the Neoadjuvant Chemotherapy Responsiveness in Breast Cancer Patients

by Igen BioLab Group | Apr 29, 2022 | News, Publications

Growing evidence supports the modulatory role of human gut microbiome on neoadjuvant chemotherapy (NAC) efficacy. However, the relationships among the gut microbiome, tumor-infiltrating lymphocytes (TILs), and NAC response for breast cancer (BC) patients remain...
Diet alters entero-mammary signaling to regulate the breast microbiome and tumorigenesis

Diet alters entero-mammary signaling to regulate the breast microbiome and tumorigenesis

by Igen BioLab Group | Jun 14, 2021 | Publications

Obesity and poor diet often go hand-in-hand, altering metabolic signaling and thereby impacting breast cancer risk and outcomes. We have recently demonstrated that dietary patterns modulate mammary microbiota populations. An important and largely open question is...
Intestinal microbiota influences clinical outcome and side effects of early breast cancer treatment

Intestinal microbiota influences clinical outcome and side effects of early breast cancer treatment

by Igen BioLab Group | May 27, 2021 | Publications

The prognosis of early breast cancer (BC) relies on cell autonomous and immune parameters. The impact of the intestinal microbiome on clinical outcome has not yet been evaluated. Shotgun metagenomics was used to determine the composition of the fecal microbiota in 121...

Recent Posts

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  • The interplay between the intratumoural microbiome, the type of cancer inflammation and the response to immunotherapy
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