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Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade

Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade

by Igen BioLab Group | Jul 19, 2021 | Publications

Treatment with combined immune checkpoint blockade (CICB) targeting CTLA-4 and PD-1 is associated with clinical benefit across tumor types, but also a high rate of immune-related adverse events. Insights into biomarkers and mechanisms of response and toxicity to CICB...

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